Process oriented guided inquiry learning (POGIL), is a group-learning method that contributes to the active participation of learners in learning/teaching environments. However, a standard process for using the POGIL in classes is not available. In addition, no systematic reviews using bibliometric analysis in the literature examine the studies concerning POGIL in terms of content and research trends. From this viewpoint, this study aimed to examine the documents related to POGIL with the bibliometric analysis method to contribute to the development of POGIL. It analyses the publications made about POGIL in the period between 1999 and 2023. A total of 179 publications available on the Web of Science were included in the study. It was found following the analyses that the publications were made in various research areas and were published in several journals. They were mostly published in the USA and the researcher with the greatest number of publications was Clifton L. Kussmaul.